About Us

Prof. Vitaliy Khutoryanskiy

Professor of Formulation Science at Reading School of Pharmacy, with PhD in Polymer Science and 25 years of research experience in the area of drug delivery and biomedical applications. He published over 200 original research papers, reviews and book chapters; filed several patent applications; edited 5 books; supervised 35 PhD students and collaborated with many industrial partners.

Dr. Roman Moiseev

Lecturer in Pharmaceutics at the University of Reading School of Pharmacy and a Visiting Lecturer at the University of Surrey School of Medicine. Dr Moiseev is a Medical Doctor and Ophthalmologist with a PhD in Pharmacy focused on designing and evaluating nanoparticles and emulsions for ocular drug delivery and assessment of various ocular models (University of Reading). He is an expert in clinical ophthalmology and ocular research with high-quality publications and excellent citation metrics. He supervises PhD, MSc, BSc Pharmacology, Pharmaceutical Chemistry, MPharm (Pharmacy), and MPAS (Physician Associate) students. 

1. Solid Dispersions for Drug Delivery: Applications and Preparation Methods
Vitaliy Khutoryanskiy and Hisham Al-Obaidi  
https://www.mdpi.com/books/book/4817-solid-dispersions-for-drug-delivery-applications-and-preparation-methods
 
2. Advances in Mucoadhesive Polymers and Formulations for Transmucosal Drug Delivery
Vitaliy Khutoryanskiy
https://www.mdpi.com/books/book/2235-advances-in-mucoadhesive-polymers-and-formulations-for-transmucosal-drug-delivery
 
3. Temperature-Responsive Polymers: Chemistry, Properties, and Applications
Vitaliy V. Khutoryanskiy and Theoni K. Georgiou
https://www.wiley.com/en-fr/Temperature+Responsive+Polymers:+Chemistry,+Properties,+and+Applications-p-9781119157786
 
4. Mucoadhesive Materials and Drug Delivery Systems
Vitaliy V. Khutoryanskiy
https://www.wiley.com/en-gb/Mucoadhesive+Materials+and+Drug+Delivery+Systems-p-9781118794395
 
5. Hydrogen-Bonded Interpolymer Complexes: Formation, Structure And Applications
Vitaliy V. Khutoryanskiy and Georgios Staikos
https://www.worldscientific.com/worldscibooks/10.1142/6498#t=aboutBook
1. Superporous hydrogels, methods of making the same, and articles incorporating the same
Enrica Caló, Lucy Ballamy, Vitaliy V. Khutoryanskiy
https://patents.google.com/patent/US20200324019A1/en
 
2. Hydrogel synthesis
Vitaliy Khutoryanskiy, Olga Khutoryanskaya, Joseph Peter Cook, Glenn William Goodall
https://patents.google.com/patent/US20130018110A1/en
 
3. Transport of cells in hydrogels
Che John Connon, Richard Anthony Cave, Vitaliy Khutoryanskiy, Bernice Wright
https://patents.google.com/patent/US10655120B2/en
1. Dynamic light scattering and transmission electron microscopy in drug delivery: a roadmap for correct characterization of nanoparticles and interpretation of results
Sergey K. Filippov, Ramil Khusnutdinov, Anastasiia Murmiliuk, Wali Inam, Lucia Ya. Zakharova, Hongbo Zhang, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/D3MH00717K

2. Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases
Adaeze Linda Onugwu, Chinekwu Sherridan Nwagwu, Obinna Sabastine Onugwu, Adaeze Chidiebere Echezona, Chinazom Precious Agbo, Stella Amarachi Ihim, Prosper Emeh, Petra Obioma Nnamani, Anthony Amaechi Attama, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.jconrel.2023.01.018
 
3. Oral care product formulations, properties and challenges
Sam R. Aspinall, Jane K. Parker, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.colsurfb.2021.111567
 
4. Thiolated Nanoparticles for Biomedical Applications: Mimicking the Workhorses of Our Body
Nathalie Hock, Giuseppe Francesco Racaniello, Sam Aspinall, Nunzio Denora, Vitaliy V. Khutoryanskiy, Andreas Bernkop-Schnürch
https://doi.org/10.1002/advs.202102451
 
5. Silica Nanoparticles in Transmucosal Drug Delivery
Twana Mohammed M. Ways, Keng Wooi Ng, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/pharmaceutics12080751
 
6. Penetration Enhancers in Ocular Drug Delivery
Roman V. Moiseev, Peter W. J. Morrison, Fraser Steele, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/pharmaceutics11070321
 
7. Progress and Current Trends in the Synthesis of Novel Polymers with Enhanced Mucoadhesive Properties
Ruairí P. Brannigan, Vitaliy V. Khutoryanskiy
https://doi.org/10.1002/mabi.201900194
 
8. Chitosan and Its Derivatives for Application in Mucoadhesive Drug Delivery Systems
Twana Mohammed M. Ways, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/polym10030267
 
9. Beyond PEGylation: Alternative surface-modification of nanoparticles with mucus-inert biomaterials
Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.addr.2017.07.015
 
10. Advances in intravesical drug delivery systems to treat bladder cancer
Oluwadamilola M. Kolawole, Wing Man Lau, Hugh Mostafid, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2017.08.120
 
11. Mucoadhesion: A food perspective
Sarah L. Cook, Stephanie P. Bull, Lisa Methven, Jane K. Parker, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.foodhyd.2017.05.043
 
12. Mucoadhesion and mucosa-mimetic materials—A mini-review
Michael T.Cook, Vitaliy V.Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2015.09.064
 
13. Biomedical applications of hydrogels: A review of patents and commercial products
Enrica Caló, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.eurpolymj.2014.11.024
 
14. Advances in ophthalmic drug delivery
Peter WJ Morrison, Vitaliy V Khutoryanskiy
https://doi.org/10.4155/tde.14.75
 
15. Microencapsulation of probiotics for gastrointestinal delivery
Michael T. Cook, George Tzortzis, Dimitris Charalampopoulos, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.jconrel.2012.06.003
 
1. Exploring Mucoadhesive and Toxicological Characteristics Following Modification of Linear Polyethylenimine with Various Anhydrides
Manfei Fu, Roman V. Moiseev, Matthew Hyder, Wayne Hayes, Silvia Amadesi, Adrian C. Williams, and Vitaliy Khutoryanskiy 
https://doi.org/10.1021/acs.biomac.4c00220

2. On the mucoadhesive properties of synthetic and natural polyampholytes
Manfei Fu, Sergey K. Filippov, Adrian C. Williams, and Vitaliy Khutoryanskiy 
https://doi.org/10.1016/j.jcis.2023.07.163

3. In vitro and in vivo toxicity of thiolated and PEGylated organosilica nanoparticles
Balnur A Zhaisanbayeva, Ellina A Mun, Leila Ulmanova, Zarina Zhunissova, Bauyrzhan Umbayev, Farkhad Olzhayev, Ivan A Vorobjev, Gonzalo Hortelano, and Vitaliy Khutoryanskiy 
https://doi.org/10.1016/j.ijpharm.2024.123852

4. Enhancing mucoadhesive properties of gelatin through chemical modification with unsaturated anhydrides
Elvira O Shatabayeva, Daulet B Kaldybekov, Leila Ulmanova, Balnur A Zhaisanbayeva, Ellina A Mun, Zarina A Kenessova, Sarkyt E Kudaibergenov, and Vitaliy Khutoryanskiy 
https://doi.org/10.1021/acs.biomac.3c01183
 
5. Mucoadhesive pickering nanoemulsions via dynamic covalent chemistry
Saul J. Hunter, Mahmoud H. Abu Elella, Edwin C. Johnson, Laura Taramova, Emma E. Brotherton, Steven P. Armes, Vitaliy V. Khutoryanskiy, Mark J. Smallridge
https://doi.org/10.1016/j.jcis.2023.07.162

6. Preparation of mucoadhesive methacrylated chitosan nanoparticles for delivery of ciprofloxacin
Renas Rzgar Jalal, Twana Mohammed M. Ways, Mahmoud H. Abu Elella, Diyar Ahmed Hassan, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijbiomac.2023.124980

7. Pickering Emulsions Stabilised with Oligoglycine-Functionalised Nanodiamond as a Model System for Ocular Drug Delivery Applications
Zhiwei Huang, Roman V. Moiseev, Solomon S. Melides, Wooli Bae, Izabela Jurewicz, Vitaliy V. Khutoryanskiy, Joseph L. Keddie
https://doi.org/10.1039/D3SM00495C
 
8. Hydroxyethyl cellulose functionalised with maleimide groups as a new excipient with enhanced mucoadhesive properties
Fhataheya Buang, Manfei Fu, Afroditi Chatzifragkou, Mohd Cairul Iqbal Mohd Amin, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2023.123113
 
9. Formation of Supramolecular Gels from Host–Guest Interactions between PEGylated Chitosan and α‐Cyclodextrin
Kalliopi-Kelli A. Vandera, Charlotte Pague, Jasmin Omar, Gustavo González-Gaitano, Twana Mohammed M. Ways, Vitaliy V. Khutoryanskiy, Cécile A. Dreiss
https://doi.org/10.1002/mame.202200646
 
10. Surface modification of silica particles with adhesive functional groups or their coating with chitosan to improve the retention of toothpastes in the mouth
Sam R. Aspinall, Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/acs.langmuir.2c03269
 
11. Synthesis of methacryloylated hydroxyethylcellulose and development of mucoadhesive wafers for buccal drug delivery
Fhataheya Buang, Afroditi Chatzifragkou, Mohd Cairul Iqbal Mohd Amin, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/polym15010093
 
12. Synthesis and evaluation of poly (3-hydroxypropyl ethylene-imine) and its blends with chitosan forming novel elastic films for delivery of haloperidol
Sitthiphong Soradech, Pattarawadee Kengkwasingh, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/pharmaceutics14122671
 
13. Mucus-penetrating nanoparticles based on chitosan grafted with various non-ionic polymers: Synthesis, structural characterisation and diffusion studies
Twana Mohammed M. Ways, Sergey K. Filippov, Samarendra Maji, Mathias Glassner, Michal Cegłowski, Richard Hoogenboom, Stephen King, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.jcis.2022.06.126
 
14. Maleimide-decorated PEGylated mucoadhesive liposomes for ocular drug delivery
Roman V. Moiseev, Daulet B. Kaldybekov, Sergey K. Filippov, Aurel Radulescu, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/acs.langmuir.2c02086
 
15. Physically cross-linked cryogels of linear polyethyleneimine: influence of cooling temperature and solvent composition
Sitthiphong Soradech, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/acs.macromol.2c01308
 
16. Development and optimization of solid lipid nanoparticles coated with chitosan and poly (2-ethyl-2-oxazoline) for ocular drug delivery of ciprofloxacin
Adaeze L. Onugwu, Anthony A. Attama, Petra O. Nnamani, Sabastine O. Onugwu, Ebele B. Onuigbo, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.jddst.2022.103527
 
17.Polyaphron formulations stabilised with different water-soluble polymers for ocular drug delivery
Roman V. Moiseev, Fraser Steele, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/pharmaceutics14050926
 
18. Polymer Architecture Effects on Poly(N,N-Diethyl Acrylamide)-b-Poly(Ethylene Glycol)-b-Poly(N,N-Diethyl Acrylamide) Thermoreversible Gels and Their Evaluation as a Healthcare Material
Peter J. Haddow, Marcelo A. da Silva, Daulet B. Kaldybekov, Cecile A. Dreiss, Ewelina Hoffman, Victoria Hutter, Vitaliy V. Khutoryanskiy, Stewart B. Kirton, Najet Mahmoudi, William J. McAuley, Michael T. Cook
https://doi.org/10.1002/mabi.202100432
 
19. Polymeric iodophors with poly (2-ethyl-2-oxazoline) and poly (N-vinylpyrrolidone): Optical, hydrodynamic, thermodynamic, and antimicrobial properties
Danelya N. Makhayeva, Sergey K. Filippov, Sanzhar S. Yestemes, Galiya S. Irmukhametova, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.eurpolymj.2022.111005
 
20. Investigation of the thermogelation of a promising biocompatible ABC triblock terpolymer and its comparison with pluronic F127
Anna P. Constantinou, Valeria Nele, James J. Doutch, Joana S. Correia, Roman V. Moiseev, Martina Cihova, David C. A. Gaboriau, Jonathan Krell, Vitaliy V. Khutoryanskiy, Molly M. Stevens, and Theoni K. Georgiou
https://doi.org/10.1021/acs.macromol.1c02123
 
21. Aldehyde-functional thermoresponsive diblock copolymer worm gels exhibit strong mucoadhesion
Emma E. Brotherton, Thomas J. Neal, Daulet B. Kaldybekov, Mark J. Smallridge, Vitaliy V. Khutoryanskiy, Steven P. Armes
https://doi.org/10.1039/D2SC02074B
 
22. Role of mucoadhesive polymers in retention of toothpaste in the oral cavity
Sam R. Aspinall, Jane K. Parker, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.colsurfb.2021.112104
 
23. Synthesis and evaluation of methacrylated poly (2-ethyl-2-oxazoline) as a mucoadhesive polymer for nasal drug delivery
Xiaoning Shan, Sam Aspinall, Daulet B. Kaldybekov, Fhataheya Buang, Adrian C. Williams, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/acsapm.1c01097
 
24. Understanding the temperature induced aggregation of silica nanoparticles decorated with temperature-responsive polymers: Can a small step in the chemical structure make a giant leap for a phase transition?
Edward D.H.Mansfield, Sergey K. Filippov, Victor R. de la Rosa, Michael T. Cook, Isabelle Grillo, Richard Hoogenboom, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.jcis.2021.01.044
 
25. Mutual Effects of Hydrogen Bonding and Polymer Hydrophobicity on Ibuprofen Crystal Inhibition in Solid Dispersions with Poly(N-vinyl pyrrolidone) and Poly(2-oxazolines)
Xiaoning Shan, Maryam A. Moghul, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/pharmaceutics13050659
 
26. A novel polymer insect repellent conjugate for extended release and decreased skin permeation of para-menthane-3, 8-diol
Sayyed I. Shah, Vitaliy V. Khutoryanskiy, Adrian C. Williams
https://doi.org/10.3390/pharmaceutics13030403
 
27. Electrosprayed mucoadhesive alginate-chitosan microcapsules for gastrointestinal delivery of probiotics
Linh Phuong Ta, Erika Bujna, Szilárd Kun, Dimitris Charalampopoulos, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2021.120342
 
28. Thiolated and PEGylated silica nanoparticle delivery to hair follicles
Jamila H. Al Mahrooqi, Vitaliy V. Khutoryanskiy, Adrian C. Williams
https://doi.org/10.1016/j.ijpharm.2020.120130
 
29. Planarian toxicity fluorescent assay: A rapid and cheap pre-screening tool for potential skin irritants
Syed Ibrahim Shah, Adrian C. Williams, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.tiv.2020.105004
 
30. Polymer structure and property effects on solid dispersions with haloperidol: Poly (N-vinyl pyrrolidone) and poly (2-oxazolines) studies
Xiaoning Shan, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2020.119884
 
31. Synthesis of hydrolytically and oxidation‐responsive networks using thiol‐ene “click” chemistry with pentaerythritol tetrakis (3‐mercaptopropionate) and tri/tetra‐acrylates
Diara S. Kazybayeva, Galiya S. Irmukhametova, Vitaliy V. Khutoryanskiy
https://onlinelibrary.wiley.com/doi/10.1002/pat.5147
 
32. Rainfastness of agrochemical formulations based on N-vinyl pyrrolidone polymers and their interpolymer complexes with poly (acrylic acid)
Apostolos A. Sevastos, Niall R. Thomson, Christopher Lindsay, Faheem Padia, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.eurpolymj.2020.109852
 
33. Development of chitosan-coated agar-gelatin particles for probiotic delivery and targeted release in the gastrointestinal tract
Hanady A. Albadran, Andrea Monteagudo-Mera, Vitaliy V. Khutoryanskiy, Dimitris Charalampopoulos
https://doi.org/10.1007/s00253-020-10632-w
 
34. Chitosan/Poly(2-ethyl-2-oxazoline) Films with Ciprofloxacin for Application in Vaginal Drug Delivery
Guzel K. Abilova, Daulet B. Kaldybekov, Galiya S. Irmukhametova, Diara S. Kazybayeva, Zhanar A. Iskakbayeva, Sarkyt E. Kudaibergenov, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/ma13071709
 
35. Chitosan/β-glycerophosphate in situ gelling mucoadhesive systems for intravesical delivery of mitomycin-C
Oluwadamilola M. Kolawole, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpx.2019.100007
 
36. Maleimide-functionalised PLGA-PEG nanoparticles as mucoadhesive carriers for intravesical drug delivery
Daulet B. Kaldybekov, Sergey K. Filippov, Aurel Radulescu, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ejpb.2019.08.007
 
37. Synthesis and evaluation of boronated chitosan as a mucoadhesive polymer for intravesical drug delivery
Oluwadamilola M. Kolawole, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.xphs.2019.05.006
 
38. Chitosan/poly(2-ethyl-2-oxazoline) films for ocular drug delivery: Formulation, miscibility, in vitro and in vivo studies
Guzel K. Abilova, Daulet B. Kaldybekov, Elvira K. Ozhmukhametova, Aisulu Zh. Saimova, Diara S. Kazybayeva, Galiya S. Irmukhametova, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.eurpolymj.2019.04.016
 
39. Mucus penetrating properties of soft, distensible lipid nanocapsules
Hanpeng Chen, Edward D.H. Mansfield, Arcadia Woods, Vitaliy V. Khutoryanskiy, Ben Forbes, Stuart A. Jones
https://doi.org/10.1016/j.ejpb.2019.02.020
 
40. Methacrylated chitosan as a polymer with enhanced mucoadhesive properties for transmucosal drug delivery
Oluwadamilola M. Kolawole, Wing Man Lau, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2018.08.034
 
41. Synthesis of thiolated, PEGylated and POZylated silica nanoparticles and evaluation of their retention on rat intestinal mucosa in vitro
Twana Mohammed M. Ways, Wing Man Lau, Keng Wooi Ng, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ejps.2018.06.032
 
42. Development of surfactant-coated alginate capsules containing Lactobacillus plantarum
Hanady A. Albadran, Afroditi Chatzifragkou, Vitaliy V. Khutoryanskiy, Dimitris Charalampopoulos
https://doi.org/10.1016/j.foodhyd.2018.04.035
 
43. Supramolecular hybrid structures and gels from host–guest interactions between α-cyclodextrin and PEGylated organosilica nanoparticles
Mariana Serres-Gómez, Gustavo González-Gaitano, Daulet B. Kaldybekov, Edward D. H. Mansfield, Vitaliy V. Khutoryanskiy, José Ramón Isasi, and Cécile A. Dreiss
https://doi.org/10.1021/acs.langmuir.8b01744
 
44. Controlling the size of thiolated organosilica nanoparticles
Jamila H. Al Mahrooqi, Ellina A. Mun, Adrian C. Williams, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/acs.langmuir.8b01556
 
45. Polysaccharide food matrices for controlling the release, retention and perception of flavours
Sarah L. Cook, Lisa Methven, Jane K. Parker, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.foodhyd.2017.12.023
 
46. Formulation of Carbopol®/Poly(2-ethyl-2-oxazoline)s Mucoadhesive Tablets for Buccal Delivery of Hydrocortisone
Leire Ruiz-Rubio, María Luz Alonso, Leyre Pérez-Álvarez, Rosa Maria Alonso, Jose Luis Vilas, Vitaliy V. Khutoryanskiy
https://doi.org/10.3390/polym10020175
 
47. Mucoadhesive polysaccharides modulate sodium retention, release and taste perception
Sarah L. Cook, Samuel Woods, Lisa Methven, Jane K. Parker, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.foodchem.2017.07.134
 
48. Structure and characterisation of hydroxyethylcellulose–silica nanoparticles
Edward D. H. Mansfield, Yash Pandya, Ellina A. Mun, Sarah E. Rogers, Inbal Abutbul-Ionita, Dganit Danino, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C7RA08716K
 
49. Mucoadhesive maleimide-functionalised liposomes for drug delivery to urinary bladder
Daulet B. Kaldybekov, Prasopchai Tonglairoum, Praneet Opanasopit, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ejps.2017.09.039
 
50. Encapsulation of Lactobacillus casei into Calcium Pectinate-Chitosan Beads for Enteric Delivery
Aigerim Bepeyeva, Joao M.S. de Barros, Hanady Albadran, Aitbek K. Kakimov, Zhaynagul Kh. Kakimova, Dimitris Charalampopoulos, Vitaliy V. Khutoryanskiy
https://doi.org/10.1111/1750-3841.13974
 
51. Delivery of Riboflavin-5′-Monophosphate Into the Cornea: Can Liposomes Provide Any Enhancement Effects?
Neva Kandzija, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.xphs.2017.05.022
 
52. Enhancement and inhibition effects on the corneal permeability of timolol maleate: Polymers, cyclodextrins and chelating agents
Isabel Rodríguez, José Antonio Vázquez, Lorenzo Pastrana, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2017.06.075
 
53. A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids
Jéssica Bassi da Silva, Vitaliy V. Khutoryanskiy, Marcos L. Bruschi, Michael T. Cook
https://doi.org/10.1016/j.ijpharm.2017.06.025
 
54. Synthesis and evaluation of mucoadhesive acryloyl-quaternized PDMAEMA nanogels for ocular drug delivery
Ruairí P. Brannigan, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.colsurfb.2017.04.050
 
55. Hydrogels based on copolymers of 2-hydroxyethylmethacrylate and 2-hydroxyethylacrylate as a delivery system for proteins: Interactions with lysozyme
Ellen V. Hackl, Vitaliy V. Khutoryanskiy, Irina Ermolina
https://doi.org/10.1002/app.44768
 
56. Investigation of physicochemical properties of PVA-GANT mucoadhesive hydrogels
Nazneen Malek, Irina Ermonlina, Vitaliy V Khutoryanskiy, Ellen V Hackl
https://doi.org/10.5920/bjpharm.2017.25
 
57. Adhesion of thiolated silica nanoparticles to urinary bladder mucosa: Effects of PEGylation, thiol content and particle size
Ellina A. Mun, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2016.08.026
 
58. Rainfastness of Poly(vinyl alcohol) Deposits on Vicia faba Leaf Surfaces: From Laboratory-Scale Washing to Simulated Rain
Brett L. Symonds, Niall R. Thomson, Christopher I. Lindsay, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/acsami.6b01682
 
59. Evaluating and optimizing oral formulations of live bacterial vaccines using a gastro-small intestine model
João M.S. de Barros, Adele Costabile, Dimitrios Charalampopoulos, Vitaliy V. Khutoryanskiy, Alexander D. Edwards
https://doi.org/10.1016/j.ejpb.2016.03.010
 
60. Chitosan as a rainfastness adjuvant for agrochemicals
Brett L. Symonds, Christopher I. Lindsay, Niall R. Thomson, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C6RA23485B
 
61. Poly (vinyl alcohol)–Gantrez® AN cryogels for wound care applications
Enrica Caló, Joao Barros, Lucy Ballamy, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C6RA24573K
 
62. Maleimide-bearing nanogels as novel mucoadhesive materials for drug delivery
Prasopchai Tonglairoum, Ruairí P. Brannigan, Praneet Opanasopit, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C6TB02124G
 
63. Side chain variations radically alter the diffusion of poly (2-alkyl-2-oxazoline) functionalised nanoparticles through a mucosal barrier
Edward D. H. Mansfield, Victor R. de la Rosa, Radoslaw M. Kowalczyk, Isabelle Grillo, Richard Hoogenboom, Katy Sillence, Patrick Hole, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C6BM00375C
 
64. Antimicrobial hydrogels based on autoclaved poly (vinyl alcohol) and poly (methyl vinyl ether-alt-maleic anhydride) mixtures for wound care applications
Enrica Caló, Joao M. S. de Barros, Mar Fernández-Gutiérrez, Julio San Román, Lucy Ballamy, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C6RA08234C
 
65. Enzyme assisted extraction of chitin from shrimp shells (Litopenaeus vannamei)
Choosit Hongkulsup, Vitaliy V Khutoryanskiy, Keshavan Niranjan
https://doi.org/10.1002/jctb.4714
 
66. Yasser A. Albarkah, Rebecca J. Green, Vitaliy V. Khutoryanskiy
https://doi.org/10.1002/mabi.201500158
 
67. Longer and safer gastric residence
Vitaliy V. Khutoryanskiy
https://doi.org/10.1038/nmat4432
 
68. Enteric coated spheres produced by extrusion/spheronization provide effective gastric protection and efficient release of live therapeutic bacteria
João M.S. de Barros, Tabea Lechner, Dimitrios Charalampopoulos, Vitaliy V. Khutoryanskiy, Alexander D. Edwards
https://doi.org/10.1016/j.ijpharm.2015.06.051
 
69. Redox- and glucose-responsive hydrogels from poly(vinyl alcohol) and 4-mercaptophenylboronic acid
Zhansaya A. Nurpeissova, Sholpan G. Alimkhanova, Rauash A. Mangazbayeva, Yerengaip M. Shaikhutdinov, Grigoriy A. Mun, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.eurpolymj.2015.06.003
 
70. Stability of probiotic Lactobacillus plantarum in dry microcapsules under accelerated storage conditions
Hanady A. Albadran, Afroditi Chatzifragkou, Vitaliy V. Khutoryanskiy, Dimitris Charalampopoulos
https://doi.org/10.1016/j.foodres.2015.05.016
 
71. Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing
Michael T. Cook, Sarah L. Smith, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C5CC02428E
 
72. Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio)ethylacrylate and 2-hydroxyethylmethacrylate: novel drug delivery systems for chemotherapeutic agents to the bladder
M. T. Cook, S. A. Schmidt, E. Lee, W. Samprasit, P. Opanasopit, V. V. Khutoryanskiy
https://doi.org/10.1039/C5TB00834D
 
73. POZylation: a new approach to enhance nanoparticle diffusion through mucosal barriers
Edward D. H. Mansfield, Katy Sillence, Patrick Hole, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C5NR03178H
 
74. Evaluation of water properties in HEA–HEMA hydrogels swollen in aqueous-PEG solutions using thermoanalytical techniques
Ellen V. Hackl, Vitaliy V. Khutoryanskiy, Gustavo M. B. Tiguman, Irina Ermolina
https://doi.org/10.1007/s10973-015-4446-y
 
75. On the Barrier Properties of the Cornea: A Microscopy Study of the Penetration of Fluorescently Labeled Nanoparticles, Polymers, and Sodium Fluorescein
Ellina A. Mun, Peter W. J. Morrison, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/mp500332m
 
76. A laminated polymer film formulation for enteric delivery of live vaccine and probiotic bacteria
João M.S. de Barros, Timothy Scherer, Dimitrios Charalampopoulos, Vitaliy V. Khutoryanskiy, Alexander D. Edwards
https://doi.org/10.1002/jps.23997
 
77. Enhancement in Corneal Permeability of Riboflavin Using Calcium Sequestering Compounds
Peter W.J.Morrison, Vitaliy V.Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2014.06.007
 
78. Microencapsulation of a synbiotic into PLGA/alginate multiparticulate gels
Michael T. Cook, George Tzortzis, Dimitris Charalampopoulos, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2014.03.034
 
79. Microencapsulation of probiotic bacteria into alginate hydrogels
M. T. Cook, D. Charalampopoulos, V. V. Khutoryanskiy
https://doi.org/10.1039/9781782622055-00095
 
80. Thermodynamic and kinetic properties of interpolymer complexes assessed by isothermal titration calorimetry and surface plasmon resonance
Samuel C. Bizley, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C4SM01138D
 
81. On the role of specific interactions in the diffusion of nanoparticles in aqueous polymer solutions
Ellina A. Mun, Claire Hannell, Sarah E. Rogers, Patrick Hole, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/la4029035
 
82. Hydrogen‐Bonded Complexes and Blends of Poly (acrylic acid) and Methylcellulose: Nanoparticles and Mucoadhesive Films for Ocular Delivery of Riboflavin
Olga V. Khutoryanskaya, Peter W. J. Morrison, Serzhan K. Seilkhanov, Marat N. Mussin, Elvira K. Ozhmukhametova, Tolebai K. Rakhypbekov, Vitaliy V. Khutoryanskiy
https://doi.org/10.1002/mabi.201300313
 
83. Hollow capsules formed in a single stage via interfacial hydrogen-bonded complexation of methylcellulose with poly (acrylic acid) and tannic acid
Krystie Driver, Sara Baco, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.eurpolymj.2013.10.004
 
84. A Comparison of Thiolated and Disulfide‐C rosslinked Polyethylenimine for Nonviral Gene Delivery
Latha Aravindan, Katrina A. Bicknell, Gavin Brooks, Vitaliy V. Khutoryanskiy, Adrian C. Williams
https://doi.org/10.1002/mabi.201300103
 
85. Influence of encapsulation and coating materials on the survival of Lactobacillus plantarum and Bifidobacterium longum in fruit juices
Sawaminee Nualkaekul, Michael T. Cook, Vitaliy V. Khutoryanskiy, Dimitris Charalampopoulos
https://doi.org/10.1016/j.foodres.2013.04.019
 
86. CLSM method for the dynamic observation of pH change within polymer matrices for oral delivery
Michael T. Cook, Teedah Saratoon, George Tzortzis, Alexander Edwards, Dimitris Charalampopoulos, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/bm301569r
 
87. Investigation of milk proteins binding to the oral mucosa
Caroline A. Withers, Michael T. Cook, Lisa Methven, Margot A. Gosney, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C3FO60291E
 
88. Synthesis of thiolated and acrylated nanoparticles using thiol-ene click chemistry: towards novel mucoadhesive materials for drug delivery
Anna Štorha, Ellina A. Mun, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C3RA42093K
 
89. Cyclodextrin Mediated Enhancement of Riboflavin Solubility and Corneal Permeability
Peter W. J. Morrison, Che J. Connon, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/mp3005963
 
90. Layer-by-layer coating of alginate matrices with chitosan–alginate for the improved survival and targeted delivery of probiotic bacteria after oral administration
Michael T. Cook, George Tzortzis, Vitaliy V. Khutoryanskiy, Dimitris Charalampopoulos
https://doi.org/10.1039/C2TB00126H
 
91. Chitosan-based mucoadhesive tablets for oral delivery of ibuprofen
Ioannis A. Sogias, Adrian C. Williams, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2012.07.007
 
92. Chitosan coated alginate beads for the survival of microencapsulated Lactobacillus plantarum in pomegranate juice
Sawaminee Nualkaekul, Dominique Lenton, Michael T. Cook, Vitaliy V. Khutoryanskiy, Dimitris Charalampopoulos
https://doi.org/10.1016/j.carbpol.2012.06.073
 
93. Microencapsulation of probiotics for gastrointestinal delivery
Michael T. Cook, George Tzortzis, Dimitris Charalampopoulos, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.jconrel.2012.06.003
 
94. A flow system for the on-line quantitative measurement of the retention of dosage forms on biological surfaces using spectroscopy and image analysis
Richard A.Cave, Joseph P.Cook, Che J. Connon, Vitaliy V. Khutoryanskiy
https://doi.org/10.1016/j.ijpharm.2012.02.047
 
95. Enhanced viability of corneal epithelial cells for efficient transport/storage using a structurally modified calcium alginate hydrogel
Bernice Wright, Richard A Cave, Joseph P Cook, Vitaliy V Khutoryanskiy, Shengli Mi, Bo Chen, Martin Leyland, Che J Connon
https://doi.org/10.2217/rme.12.7
 
96. Microwave‐assisted hydrogel synthesis: a new method for crosslinking polymers in aqueous solutions
Joseph P. Cook, Glenn W. Goodall, Olga V. Khutoryanskaya, Vitaliy V. Khutoryanskiy
https://doi.org/10.1002/marc.201100742
 
97. Optimizing layer-by-layer deposition of interpolymer complexes on solid substrates using Biacore
Samuel C. Bizley, Adrian C. Williams, Fred Kemp, Vitaliy V. Khutoryanskiy
https://doi.org/10.1039/C2SM25652E
 
98. Hydrogen-Bonding-Driven Self-Assembly of PEGylated Organosilica Nanoparticles with Poly(acrylic acid) in Aqueous Solutions and in Layer-by-Layer Deposition at Solid Surfaces
Galiya S. Irmukhametova, Brian J. Fraser, Joseph L. Keddie, Grigoriy A. Mun, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/la2038735
 
99. Thiolated Mucoadhesive and PEGylated Nonmucoadhesive Organosilica Nanoparticles from 3-Mercaptopropyltrimethoxysilane
Galiya S. Irmukhametova, Grigoriy A. Mun, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/la201385h
 
100. Production and evaluation of dry alginate-chitosan microcapsules as an enteric delivery vehicle for probiotic bacteria
Michael T. Cook, George Tzortzis, Dimitris Charalampopoulos, and Vitaliy V. Khutoryanskiy
https://doi.org/10.1021/bm200576h

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